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Automated brain MRI volumetry and T1 relaxometry in children with focal epilepsy of unknown cause.
Baptiste MOREL1,2, Anne Sophie Piegay1, Maximilien Perivier1, Sandra Obry1, Bénédicte Maréchal3,4,5, Gian Franco Piredda3,4,5, Tom Hilbert3,4,5, Tobias Kober3,4,5, Clovis Tauber6, Pierre Castelnau6, and Jean Philippe Cottier1
1CHU de Tours, Tours, France, 2UMR 1253, iBrain, Université de Tours, INSERM, Tours, France, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 4Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 5LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 6INSERM U1253, Tours, France
A postprocessing brain MRI allowed obtaining automatically both volumetry and T1 relaxometry values. It helps radiologists to quantify brain abnormalities undetected in brain MRI in more than 80% of the initial exploration of children with focal epilepsy of unknown cause.
Sagittal, axial and coronal views (line A, B and C) of the MP2RAGE sequence with the postprocessing morphometric analysis results of a 6 years girl having left focal epilepsia. UNI column is a highly contrasted T1 image. T1 relaxometry map is the second column. Morphobox column represents the brain segmentation obtained. A Volumetry and T1 relaxometry Z-score maps are also provided for a visual analysis. We noticed a decreased T1 relaxometry values in the left cortical occipital grey matter.