Virendra R Mishra1, Karthik Sreenivasan1, Dietmar Cordes1, Aaron Ritter1, and Charles Bernick2
1Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States, 2University of Washington - Seattle, Seattle, WA, United States
1Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States, 2University of Washington - Seattle, Seattle, WA, United States
Our study shows that RHI induces a topological shift that is correlated
with neuropsychological scores. Our study also suggests that there is a minimum
optimal threshold of structural connectivity as there was an inverted U-shape
pattern correlated with processing speed in controls.
Figure 1: (A): A brief flowchart
describing the generation of structural connectivity matrix for every
participant. Average symmetric
connectivity matrix for the impaired and nonimpaired group is shown. The color
map indicates the average strength of connections between any two nodes in the
connectivity matrix. (B): Paths showing weaker
structural connectivity in boxers. Nodes and edges of the paths are represented
in blue and red colors respectively. L and R represent left and right
hemisphere.
Figure 4: Rich-club regime for both HC and boxers is shown in the
shaded box. Nodes exhibiting rich-club properties are shown as yellow circles
for both boxers and HC, and non-rich-club nodes are shown as green circles.
Rich-club edge strength, feeder edge strength, and local edge strength are
plotted as bar plots for both groups. K:degree; φ-norm: normalized rich-club
coefficient