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Central vein sign occurrence on FLAIR* in neuropsychiatric systemic lupus erythematosus patients
Francesca Inglese1, Kenneth Hergaarden1, Pierre-Louis Bazin2, Gerda M. Steup-Beekman3, Tom J.W. Huizinga3, Jeroen de Bresser1, and Itamar Ronen1
1Department of radiology, Leiden University Medical Center, Leiden, Netherlands, 2Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, Netherlands, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Central vein sign lesions may not be exclusive to multiple sclerosis but appear also in other autoimmune diseases, such as systemic lupus erythematosus with NP events, in a random occurrence.
Figure 2. Each row of panels shows one of two CVS lesions seen in one SLE subject experiencing NP events in axial, sagittal and coronal planes. Inserts in white rectangles are magnified views of the lesion, circled in yellow.
Figure 1. Pipeline to generate FLAIR* images.