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Effects of vibration on cerebral blood flow using 3D arterial spin labeling imaging
Linghan Kong1, Suhao Qiu1, Zhao He1, RunKe Wang1, Yu Chen1, Qiang He2, and Yuan Feng1
1Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 2Shanghai United Imaging Healthcare Co Ltd, Shanghai, China
The cerebral blood flow after applying vibration to the brain was measuring using 3D arterial spin labeling. Results showed the vibration of brain at 30 Hz could reduce the regional and global CBF.
Figure 2: The difference of CBF in each step. The CBF values were represented by f. Compared with resting state, the regional and global mean CBF values of control state both decreased. Compared with before vibration (fA), the regional and global CBF values both decreased after two vibration (fB and fC). And compared with the first vibration, the CBF decreased greater after the second vibration.
Figure 1: An illustration of the experimental workflow. In the first step, 3D-ASL was used to measure the CBF of subjects in the resting state. Scan time was 4.5 minutes, and the scan interval was 3 minutes. Then the subjects wear an actuator (off) to be scanned with 3D-ASL again (Control). In the second step, the subjects first wear an actuator (off) to be scanned with 3D-ASL (A). And then the actuator was turned on for 5minutes. After the vibration, 3D-ASL was used again to obtain the CBF of the subjects (B). To ensure the stability of the results, the vibration and measurement was repeated (C).