Increased Saturated Fatty Acid Fraction in the Adipose Tissue Near Malignant Tumors in Breast Cancer Patients
Mehran Baboli1, Pippa Storey2, Terlika Pandit Sood2, Justin Fogarty2, Melanie Moccaldi2, Alana Lewin2, Linda Moy2, and Sungheon Gene Kim1
1Radiology, Weill Cornell Medicine, New York, NY, United States, 2Radiology, NYU Langone Health, New York, NY, United States
The
SFA was significantly higher around the malignant tumor than on the
contralateral normal breast while no significant changes were observed in
benign tumors. The results showed that the SFA could potentially be used to
understand the role of adipose tissue and the development of breast cancer
Figure 2:
Examples of the SFA maps in contra- and ipsilateral breast and small ROI around
the tumor. Only the voxels with >90% fat fraction were included in the maps.
Figure 3:
SFA comparison between contralateral, ipsilateral breast, and a small ROI
around the lesions for patients with (a) benign and (b) malignant lesions. A
significantly higher (p= 0.007) SFA was observed around the malignant lesions.