Qiang Liu1,2, Yuanbo Yang1,2, Xinyuan Zhang1,2, Yingjie Mei1,2,3, Qiqi Lu1,2, Guoxi Xie4, and Yanqiu Feng1,2
1School of Biomedical Engineering, Southern Medical University, Guangzhou, China, 2Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 3Philips Healthcare, Guangzhou, China, 4Department of Biomedical Engineering, School of Basic Sciences, Guangzhou Medical University, Guangzhou, China
1School of Biomedical Engineering, Southern Medical University, Guangzhou, China, 2Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 3Philips Healthcare, Guangzhou, China, 4Department of Biomedical Engineering, School of Basic Sciences, Guangzhou Medical University, Guangzhou, China
The present work investigated
the implement of Diffusion-Prepared 3D RARE sequence using a variable flip-angle strategy to
acquire distortion free diffusion weighted images on a small animal
pre-clinical 7 T scanner.
Figure
2 Comparisons of both non-diffusion and
diffusion weighted images of mouse brain acquired using Diffusion-prepared 3D
VF-RARE and single-shot EPI. a: T2-RARE was acquired as anatomy reference. b, c
: b=0 s/mm2 images of sequence DP VF-RARE and SS-EPI. d, e : b=500
s/mm2 images of sequence DP VF-RARE and SS-EPI.
Figure 3 Comparison of in vivo FA maps (a,
b) and color-encoded FA maps (c,d) of an adult mouse brain acquired using DP 3D
VF-RARE and SS-EPI. The areas of cortex and hippocampus were used in the
following MD’s and FA’s calculation.