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Deep learning for synthesizing high-b-value DWI of the prostate: A tentative study based on generative adversarial networks
lei hu1, jungong Zhao1,2, Caixia fu3, and Thomas Benkert4
1Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixt, 上海, China, 2Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixt, shanghai, China, 3MR Application Development, Siemens Shenzhen magnetic Resonance Ltd, shanghai, China, 4MR Application Predevelopment, Siemens Healthcare, Erlangen, Gernmany, Erlangen, Germany
A deep learning framework based on GAN is a promising method to synthesize realistic high-b-value DWI sets with good image quality and accuracy in PCa detection.  
Fig.1 Violin plots of distributions of the quantitative metrics between M0 and Mcyc.
Fig.2 T2WI, ADC, a-DWIb1000, a-DWIb1500, cal-DWIb1500, non-optimized syn-DWIb1500 vs. optimized syn-DWIb1500 of four different patients. Patient A: A 76-year-old man with chronic prostatitis. Patient B: A 63-year-old man with prostatic hyperplasia. Patient C: An 87-year-old man with prostatic cancer in the right transition zone. (Gleason score, 4+3). Patient D: A 69-year-old man with prostatic cancer in the peripheral zone invading the rectum (Gleason score 4+5).