Nabeelah Jinnah1, Olivier Mougin1, Penny Gowland1, Caroline Hoad1, Gordon Moran1, Andrew Carradus1, and Hannah Williams1
1University of Nottingham, Nottingham, United Kingdom
1University of Nottingham, Nottingham, United Kingdom
Collagen is an important contribution to tissue fibrosis. We have
characterized the z-spectrum of collagen in phantoms at 3T and 7T. We found two
peaks at +1.9 ppm and +3.5 ppm. Fitting to the Bloch McConnell equations using
a PSO algorithm yielded pool sizes that increased with
concentration.
Figure 2: Spectra
acquired at 7T at 5 different powers and
fitted using the PSO algorithm, with an acquisition time of 9s/frequency.
Figure 1: Spectra
acquired at 3T for the diverse concentration and at 3 different saturation powers and fitted using the PSO algorithm, with an acquisition time of 21s per
frequency.
