Community-informed connectomics of cortical intrinsic organization in participants with subjective cognitive decline
Qian Chen1, Jilei Zhang2, and Bing Zhang1
1Department of Radiology, Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China, 2Philips Healthcare, Shanghai, China
Individuals with subjective cognitive decline showed disruptions
in the cortical intrinsic organization of visual and dorsal attention networks
and enhanced intra-module interaction of the frontoparietal network.
Figure 2. A Distribution of cortical within-module
degree (WMD) and participation coefficient (PC) averaged across 32 normal
controls (NC). B Differences between NC (gray) and 36 participants with
subjective cognitive decline (SCD) (black). Scatterplots represent WMD/PC
values in significant clusters. Findings were adjusted for age, gender, and
years of education.
Figure 1. Gordon’s 333
cortical parcels and 10 predefined communities. AN: auditory network; DMN:
default mode network; FPN: frontoparietal network; SN: salience network; VN:
visual network; CON: cingulo-opercular network; DAN: dorsal attention network;
MTN: medial temporal network; SMN: sensorimotor network; VAN: ventral attention
network.