Zihan Zhou1, Qing Li1,2, Congyu Liao3, Xiaozhi Cao3, Ting Gong1, Qiuping Ding1, Hongjian He1, and Jianhui Zhong1,4
1Center for Brain Imaging Science and Technology, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, China, 2MR Collaboration, Siemens Healthcare Ltd, Shanghai, China, 3Radiological Sciences Laboratory, Stanford University, Stanford, CA, United States, 4Department of Imaging Sciences, University of Rochester, Rochester, NY, United States
1Center for Brain Imaging Science and Technology, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, China, 2MR Collaboration, Siemens Healthcare Ltd, Shanghai, China, 3Radiological Sciences Laboratory, Stanford University, Stanford, CA, United States, 4Department of Imaging Sciences, University of Rochester, Rochester, NY, United States
3D Ultrashort Echo Time MR Fingerprinting (UTE-MRF) sequence
can achieve whole brain myelin mapping in 15 min with 0.87 mm isotropic
resolution.
Fig. 1. 3D UTE-MRF sequence diagram 5. (a) shows the pattern of flip angles in an MRF unit. It varies among every TR. A delay time of 2000 ms between two repetitions is used. (b) shows the sequence during a TR. UTE is the first (ultrashort) echo time.
Fig. 3. 3D UTE-MRF dual echo results of a healthy volunteer (Subject 1). A: Real part of the signal curves in both WM and GM for the dual-echo images. Frame 62 is chosen as the optimum frame for myelin imaging. B: Different frame images for different contrast. (a-d) are echo 1 from frame 58, 62, 68 and 74. (e-f) are echo 2 from frame 58, 62, 68, and 74. (i-l) are echo difference from frame 58, 62, 68, and 74. (j) shows that at frame 62, the long T2 tissue is suppressed.
