Xi Chen1, Dost Ongur1, and Fei Du1
1McLean Hospital; Harvard Medical School, Belmont, MA, United States
1McLean Hospital; Harvard Medical School, Belmont, MA, United States
This
study observed that the relationship between default-mode network
neurotransmitters and the brain functional connectivity breaks down in
first-episode psychosis patients, which provides novel insights into the mechanism
of the brain network abnormalities of psychosis.
Figure 1 Seed
region of functional connectivity, MRS voxel location, and representative
spectra of semi-LASER and MEGA-PRESS (6).
Figure 4 Correlations between the
MPFC-DLPFC resting-state connectivity and MPFC GABA and Glu concentrations
respectively in schizophrenia and
healthy control groups.
