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Morphological changes of the corpus callosum in antipsychotic-naive first-episode schizophrenia before and 1-year after treatment
Bo tao1, Yuan Xiao1, Wenjing Zhang1, Na Hu1, John A Sweeney1,2, and Su Lui1
1Huaxi MR Research Center (HMRRC), Functional and molecular imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China, 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH, United States
The present study demonstrates deficits of the callosal morphology in schizophrenia, which may reflect an neurodevelopment aberration. And short-term antipsychotics may not have a significant impact on the CC morphology in the early stage of illness.  
Table 1. Demographic and clinical characteristics of AN-FES and HCs.
Table 2. Demographic and clinical characteristics of schizophrenia patient subgroups at baseline and after one-year follow-up.