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31P dual-band pulse for selective refocusing of phosphomonoesters and phosphodiesters at low B1+ and low SAR
Zahra Shams1, Evita C. Wiegers1, Wybe J.M. van der Kemp1, Dennis W.J. Klomp1, and Jannie P. Wijnen1
1Department of radiology, University Medical Center Utrecht, Utrecht, Netherlands
We designed a dual-band pulse to selectively refocus PME and PDE spins. The dual band pulse, with B1+ < 15µT, uses almost 3 times less power compared to a single band pulse, making this an attractive option for multi-echo 31P body MRSI  in cancer.
Figure 3. The spectra acquired in vivo from a pulse acquire and a spin echo acquisition with the dual band pulse aimed to hit the PDE and PME spin groups from the entire head, where B0 shimming is optimized over the yellow box. All MR spectra were displayed using a 10‐Hz Lorentzian line‐broadening filter. Note the well refocused signals of PME and PDE.
Figure 2. Spectra acquired from a phantom with a spin echo (A) and a pulse acquire (B) acquisition. The dual band pulse at the frequency offset 3 resulted in a full refocusing of the three peaks of PE, PC and GPC. All MR spectra were displayed using a 10‐Hz Lorentzian line‐broadening filter. The yellow box is the shim box.