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Liver parenchymal change after stereotactic radiotherapy for hepatocellular carcinoma using DWI  and  MRE
Yoshie Omiya1, Utaroh Motosugi2, Hiroyuki Morisaka1, and Hiroshi Onishi1
1University of Yamanashi, Yamanashi, Japan, 2Kofu-Kyoritsu Hospital, Yamanashi, Japan
Stereotactic body radiotherapy (SBRT) is a treatment option for patients with hepatocellular carcinoma (HCC). We evaluated the liver parenchymal changes after SBRT using liver stiffness with MRE and the apparent diffusion coefficient values with DWI. They were significantly elevated.
Figure2. Box plots show of the liver stiffness and ADC values in the area receiving high dose and low dose of stereotactic body radiotherapy (SBRT). Liver stiffness and ADC values were significantly increased in both areas after SBRT. Exclude cases where ROI cannot be obtained sufficiently.
Figure3. Case1: 79-year-old man with HCC at S6. The dose of SBRT was 50Gy/25Fr (PTV-95). The liver stiffnesses after SBRT were higher than those before SBRT in both area receiving >30Gy and area receiving <15Gy.