Low field 19F imaging of perfluoroctylbromide: eliminating chemical shift effects and minimizing scalar coupling signal loss
Javad Parsa1 and Andrew Webb1
1Leiden University Medical Center, Leiden, Netherlands
Low field MRI can be used to acquire 19F images with very high efficiency even for contrast agents with multiple resonances and scalar coupling, achieving very close to the theoretical SNR limit.
Figure 1.
(left) Photograph of the solenoid coil which can be switched between 1H
and 19F using a mechanical switch (arrow). (centre) Photograph of
the phantom placed in the centre of the coil. (right) Schematic of the phantom
with vials filled with water (blue), fomblin (orange) and a single tube of PFOB
(red).
Figure 2. (left) S11
plots of the 1H and 19F switched-mode RF coil. (center)
Spin-echo 1H image from the
phantom, (right) Corrsponding spin-echo 19F image.