Accelerated Dynamic MRI for the Assessment of Esophageal Peristalsis During Swallowing
Ethan M I Johnson1, Sourav Halder2, Peter J Kahrilas1, John E Pandolfino1, Neelesh A Patankar2, and Michael Markl1
1Northwestern University, Chicago, IL, United States, 2Northwestern University, Evanston, IL, United States
Time-resolved imaging of esophageal peristalsis is feasible with modified MR angiography imaging techniques and 50% concentrated pineapple juice.
Figure 2. Using a modified MR angiography sequence with view-sharing and parallel imaging acceleration, a reduction of pineapple juice (50% volume) can be clearly and dynamically visualized in the esophagus as it is transported by peristalsis (A). Juice from the 20 mL swallow is visible in the stomach during the 10 mL swallow, which was performed after the 20 mL swallow. Renders of the bolus created by seeded region-growing image intensity thresholding are shown next to MIPs for each time frame. Peristalsis is not well visualized by a swallow of raw pineapple juice (B).
Figure 1. A plot of the measured T1 in pineapple juice at various volume-reduction factors (left) depicts the log-linear relationship between juice T1 reduction and juice volume reduction (right). The dashed line shows a one-to-one log-linear relationship for reference, and the solid line shows the empirical fit. The Pearson correlation coefficient for juice T1 reduction vs. volume reduction is 0.996 (p<0.001).