1916

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Brain rejuvenation improves accuracy of automatic segmentation of the aged brain

Roman Fleysher¹, Mohammad Mansouri¹, and Michael L Lipton¹
¹Radiology, Albert Einstein College of Medicine, Bronx, NY, United States

We propose and demonstrate “brain rejuvenation” as a method to improve accuracy of automatic segmentation of the aged brain.

Figure 3. Worsening of atlas quality with increased simulated brain atrophy indexed by the age of the target elderly brain. Distance is measured with respect to the gold atlas (see Figure 1).

Figure 4. Sensitivity to simulated brain atrophy is resolved when using brain rejuvenation (Figure 2) before FreeSurfer.