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Investigation of brain regional relaxation characteristics in healthy subjects during normal aging using synthetic MRI
Di Wang1, Lu Yu2, Pu-Yeh Wu3, Chunmei Li2, and Min Chen2
1Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, P.R. China, Bejing, China, 2Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, P.R. China, Beijing, China, 3GE Healthcare, Beijing, China, Beijing, China
We adopted Synthetic MRI to investigate the age-related relaxation characteristics changes in healthy subjects by brain region-based analysis. We found significant differences of relaxation characteristics between bilateral hemispheres,T1, T2 and PD showed a quadratic trend with age.
Table 1. Comparison of left and right hemispheres(genu and splenium of corpus callosum) among the relaxation times