Masoumeh Dehghani1,2 and Jamie Near1,2
1McGill university, Montreal, QC, Canada, 2Centre d'Imagerie Cérébrale, Douglas Mental Health University, Montreal, QC, Canada
1McGill university, Montreal, QC, Canada, 2Centre d'Imagerie Cérébrale, Douglas Mental Health University, Montreal, QC, Canada
- Demonstrated feasibility of performing simultaneous 1H MRS localization at multiple brain regions using dual-Special sequence
- Revealed interregional significant differences between anterior and posterior cingulate cortices, and medial supplementary motor area and adjacent lateral WM
Figure
1. (a)
Three-dimensional T1-weighted anatomical images were acquired using
MPRAGE. Green boxes covering two voxels illustrate the shimming
volume in first scan. ACC (blue box) and PCC (red box) regions were selected for 1H
MRS acquisition. (b) Localized water
suppressed 1H spectrum (blue) along with
spectral fit (orange), residual (black) and baseline (red) obtained from
LCModel quantification.
Figure
2. (a) Green boxes covering two voxels illustrate the
shimming volume in second scan in the anatomical MPRAGE
image. GM-rich (red box) and WM-rich (blue box)
regions were selected for 1H MRS acquisition. (b) Localized water
suppressed 1H spectrum (blue) along with
spectral fit (orange), residual (black) and baseline (red) obtained from
LCModel quantification.