Adam Berrington1, Joseph S Gillen2,3, and Vincent Boer4
1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United Kingdom, 3F.M. Kirby Research Centre, Kennedy Krieger Institute, Baltimore, MD, United States, 4Danish Research Centre for Magnetic Resonance,Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark
1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United Kingdom, 3F.M. Kirby Research Centre, Kennedy Krieger Institute, Baltimore, MD, United States, 4Danish Research Centre for Magnetic Resonance,Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital, Hvidovre, Denmark
An optimized GOIA-WURST(50,10)
inversion pulse shape was found to improve off resonance inversion profile for
low B1 field (15 μT) at 4.5 ms and reduced the minimum echo time at ultra-high
field for semi-LASER to 23 ms.
Fig.2: Simulated inversion
profiles for a) HS b) FOCI5 c) GOIA-W(16,4) and GOIA-W(50,10) at 15 μT maximum
B1 field and for 0,1 and 2 ppm off-resonance at 7T. GOIA-W(50,10) shows
compromise between passband ripple and CSD for 4.5ms.
Fig.4: Single-voxel
semi-LASER MRS on a brain metabolite phantom (after line broadening) using
three different adiabatic inversion pulses a) GOIA-W(50,10) b) FOCI5 and c) HS
resulting in a minimum echo time of 23, 31 and 37 ms respectively.