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Dynamic contrast enhanced imaging (DCE-MRI) combined with T1 and T2 mapping for differentiation between HCC and HM

Lili Fan¹, Ailian Liu¹, Jiazheng Wang², Liangjie Lin², Lihua Chen¹, Qingwei Song¹, Renwang Pu¹, Ying Zhao¹, Tao Lin¹, and Xue Ren¹
¹The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

Dynamic contrast enhanced imaging (DCE-MRI) combined with T1 and T2 mapping showed a high efficacy to distinguish hepatocellular carcinoma (HCC) from hepatic metastasis (HM) (AUC: 0.936; sensitivity: 81.8%; specificity: 100%).

Figure 3. ROC curves of DCE, T1/T2mapping, and the combine.

Figure 1. A 61-year-old male with HCC. Ktrans map (a), Kep map (b), Ve map (c), Vp map (d), T1 mapping (e), T2 mapping (f), T2WI (g).

Figure 2. A 65-year-old female patient with HM. Ktrans map (a), Kep map (b), Ve map (c), Vp map (d), T1 mapping (e), T2 mapping (f), T2WI (g).