Ralph E. Hurd1, Meng Gu1, Phil Adamson2, Kirk Riemer3, Ryan Beckman3, Michael Ma3, Kenichi Okamura3, Frank Hanley3, and Daniel Spielman1
1Radiology, Stanford, Stanford, CA, United States, 2Electrical Engineering, Stanford, Stanford, CA, United States, 3Cardiothoracic Surgery, Stanford, Stanford, CA, United States
1Radiology, Stanford, Stanford, CA, United States, 2Electrical Engineering, Stanford, Stanford, CA, United States, 3Cardiothoracic Surgery, Stanford, Stanford, CA, United States
A dominant, but manageable residual water signal in MR spectroscopy provides substantial value. A residual water-by-design strategy should be considered in sequence and protocol design.
Figure 2. Baseline 37°C spectrum after PWS to 1% residual water. Good fidelity observed for nearest neighbors, the C1α of glucose and the anomeric proton of NAA. Spectral baseline for normal fit region above 4.2 ppm is unperturbed.
Figure 4. 37C Circulatory arrest. Powder-pattern develops during circulatory arrest and resolves after 5 minutes of recovery. The residual water reveals low level powder pattern which provides a measure of deoxy-Hb and hypoxia. Glucose recovers but lactate persists after hypoxia reversed.
