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Macromolecule suppressed GABA levels show no relationship with age in children and adolescents
Tiffany Bell1,2,3, Mehak Stokoe1,2,3, and Ashley Harris1,2,3
1Department of Radiology, University of Calgary, Calgary, AB, Canada, 2Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada, 3Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada
There were no significant correlations between age (7-14 years) and macromolecule-suppressed GABA levels in the thalamus, sensorimotor and occipital cortices when using either water (i.e., molal units) or creatine referencing.
Figure 2:Correlations between the three versions of macromolecule-suppressed GABA levels and age. a) Correlation between macromolecule-suppressed GABA and age. b) Correlation between α-corrected macromolecule-suppressed GABA and age. c) Correlation between macromolecule-suppressed GABA/Cr and age. TH: Thalamus (red); SM: Sensorimotor Cortex (green); OC: Occipital Cortex (blue); MM Supp : macromolecule-suppressed.
Table 1: Correlations between macromolecule-suppressed GABA measures and age (months)