2247
Grading of pediatric intracranial tumors: are intravoxel incoherent motion and diffusion kurtosis imaging superior to conventional DWI?
dejun she1, dairong cao1, shan lin1, zhongshuai zhang2, and Robert Grimm3
1The First Affiliated Hospital of Fujian Medical University, Fujian Fuzhou, China, 2SIEMENS healthcare diagnostic imaging, Shanghai, Pudong, Zhouzhu Highway 278, China, 3SIEMENS Healcare, Erlangen, Germany
To explore the correlations between parameters derived from conventional diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and diffusion kurtosis imaging (DKI) with histopathologic features of pediatric intracranial tumors.
A 15-year-old boy with medulloblastoma in cerebellum (WHO grade Ⅳ). The lesion shows hyperintense on T2-weighted image(a), hypointense on T1-weighted image (b), and enhancement on post-contrast T1-weighted image (c). The lesion (ROI) demonstrates hypointense on the ADC map (d), D map (e), and Dk map (h), and hyperintense on the D* map (f), f map (g), and K map (i). The pathologic diagnosis was medulloblastoma with high cellularity of 4928(cell/mm2)(j), high Ki-67 index of 80% (k), and MVD of 1.4% (l) (magnification, × 200).
A 5-year-old boy with diffuse astrocytoma in brainstem (WHO grade II). The lesion shows hyperintense on T2-weighted image(a), hypointense on T1-weighted image (b), and enhancement on post-contrast T1-weighted image (c). The lesion (ROI) demonstrates hyperintense on the ADC map (d), D map (e), and Dk map (h), and hypointense on the D* map (f), f map (g), and K map (i). The pathologic diagnosis was diffuse astrocytoma with high cellularity of 1918(cell/mm2) (j), high Ki-67 index of 1.1% (k), and MVD of 0.9% (l) (magnification, × 200).