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R2* value derived from multi-echo Dixon technique can aid discrimination between benign and malignant focal liver lesions
Guangzi Shi1, Hong Chen1, Weike Zeng1, Mengzhu Wang2, and Jun Shen1
1Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, 2Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, China
R2* value of malignant FLLs was significantly higher than that of the benign FLLs. R2* derived from multi-echo Dixon imaging is a potential biomarker to differentiate malignant from benign FFLs.
Figure 1. 2D region of interest (2D-ROI) and volume of interest (VOI). T2-weighted imaging (T2WI) (A) and arterial phase contrast-enhanced T1-weighted imaging (T1WI) (B), and R2* map (C) show liver metastasis (yellow line) confirmed by histology in a 59-year-old woman with lung cancer. T2WI (E) and arterial phase contrast-enhanced T1WI (F), and R2* map (G) show a live hemangioma (yellow line) in in a 59-year-old woman. (D) 2D-ROI was drawn on the section showing the maximal tumor dimension. (H) VOI was placed covering the entire tumor volume on R2* map.
Figure 4. Receiver operating characteristic curve analysis of the two positioning methods in differentiating between malignant group and benign group. 2D region of interest (2D-ROI) and volume of interest (VOI) methods yielded the similar results.