Junko Kikuta1, Koji Kamagata1, Kaito Takabayashi1, Toshiaki Taoka2, Hajime Yokota3, Yuki Someya4, Yoshifumi Tamura4,5, Hirotaka Watada4,5, Ryuzo Kawamori4,5, Shinji Naganawa6, and Shigeki Aoki1
1Department of Radiology, Juntendo University School of Medicine, Bunkyo-ku, Japan, 2Department of Innovative Biomedical Visualization, Graduate School of Medicine, Nagoya University, Nagoya, Japan, 3Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, 4Sportology Center, Juntendo University School of Medicine, Bunkyo-ku, Japan, 5Department of Metabolism & Endocrinology, Juntendo University School of Medicine, Bunkyo-ku, Japan, 6Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
1Department of Radiology, Juntendo University School of Medicine, Bunkyo-ku, Japan, 2Department of Innovative Biomedical Visualization, Graduate School of Medicine, Nagoya University, Nagoya, Japan, 3Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, 4Sportology Center, Juntendo University School of Medicine, Bunkyo-ku, Japan, 5Department of Metabolism & Endocrinology, Juntendo University School of Medicine, Bunkyo-ku, Japan, 6Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan
We used the analysis along the perivascular space (ALPS) index, which has been
suggested as a noninvasive method to
measure water diffusivity along the perivascular space in vivo. We assessed the change in water diffusivity in living
patients with hypertension for the first time.
Fig.2. Region of interest (ROI) placement for the manual-based ALPS index
A 5-mm-diameter spherical ROI was placed in the projection and association areas.
Fig.3. The Box plot of the ALPS index
The ALPS index in the HT group was significantly lower than that in the control group (p value < 0.05).