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Renal hypoxia estimated by O2-inhalation T2* BOLD MRI: association with renal dysfunction and left ventricular remodeling in cardiomyopathy

Michinobu Nagao¹, Kiyoe Ando¹, Yasuhiro Goto¹, Isao Shiina¹, Kazuo Kodaira¹, Masami Yoneyama², Takashi Namiki², Atsushi Yamamoto¹, Eri Watanabe¹, Akiko Sakai¹, Risako Nakao¹, and Shuji Sakai¹
¹Tokyo Women's Medical University, Tokyo, Japan, ²Philips Japan, Tokyo, Japan

O2-inhalation T2*-BOLD MRI is a non-invasive imaging techniqueto evaluate renal oxygenation. Renal hypoxia expressed as decreased ΔR2*ratio is strongly associated with reduced eGFR. Early LV remodeling can lead to renal hypoxia.

O2-inhalation T2* BOLD MRIR2* map for 67 years man with cardiomyopathy and mild renal dysfunction

Comparison of ΔR2*ratio between patients with eGFR <50mL/min/1.73m2and >50 mL/min/1.73m2(left) and between patient with LVEDVi >95 ml/m2 and <95 ml/m2.