Alexandra Grace Roberts1,2, Pascal Spincemaille2, Thanh Nguyen2, and Yi Wang2,3
1Electrical and Computer Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell, New York, NY, United States, 3Biomedical Engineering, Cornell University, Ithaca, NY, United States
1Electrical and Computer Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell, New York, NY, United States, 3Biomedical Engineering, Cornell University, Ithaca, NY, United States
Morphology Enabled Dipole Inversion
(MEDI-d) is an iterative reconstruction algorithm for Quantitative Susceptibility
Mapping (QSM) that is effective in suppressing shadow artifacts by exploiting
the downsampled magnitude image as a morphological prior.
Figure 1. Original structural weighting matrix
(left) and downsampled structural weighting matrix (right) in the $$$x$$$-direction. Note
that the white regions (equal to 1) enforce edge requirements on the
susceptibility solution while the black regions (equal to 0) do not.
Figure 2. Central slice of control MEDI, MEDI-d with a downsampling factor of 2 and 3 different
regularization parameters, and MEDI-SMV. Note the reduction of shadowing causes
loss of detail that occurs beyond $$$\lambda_2$$$ = 1000.
