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Differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy by texture analysis of T2-weighted CMR imaging
Shan Huang1, Yuan Li1, Ke Shi1, Yi Zhang1, Ying-kun Guo2, and Zhi-gang Yang1
1Radiology, West China Hospital, Chengdu, China, 2Radiology, West China Second University Hospital, Chengdu, China
Texture analysis was feasible and reproducible for detecting myocardial tissue alterations on T2-weighted images. Our radiomics model had a great performance in differentiating between CA and HCM patients, which was comparable to LGE.

Figure1 Feature selection and dimension reduction process.

ICC: intraclass correlation coefficient, LASSO: the least absolute shrinkage and selection operator.

Figure 2 Correlogram of the relationship among the selected texture features.

Smaller and/or lighter circles represent lower correlation. On the contrary, larger and/or darker circles indicate higher correlation. GLRLM: gray level run length matrix, GLDM: gray level dependence matrix, GLCM: gray level co-occurrence matrix; LRE: Long Run Emphasis; SRE: Short Run Emphasis; SDHGLE: Small Dependence High Gray Level Emphasis; LDE: Large Dependence Emphasis; H: high wavelet filter; L: low wavelet filter