Ultra-fast arterial spin labeling with narrow-band velocity-selective (nb-VS) labeling
Jia Guo1
1Bioengineering, University of California Riverside, Riverside, CA, United States
Modeling results showed that the SNR efficiency and temporal
resolution of perfusion imaging could be greatly improved if a narrow-band
velocity selectivity can be realized. We introduced modified FT-based VSI pulses
that are suitable for this purpose and ultra-fast perfusion imaging.
Figure 1.
Schematics showing that narrow-band velocity selectivity allows ultra-fast
perfusion imaging with high SNR efficiency, while conventional VSASL (wide-band
labeling) may suffer from reduced SNR efficiency due to multiple labeling on
the same bolus.
Figure 3. The
velocity-selective profiles under the label condition for both modified
rect-VSI and sinc-VSI labeling. Under the control condition, the magnetization response
was the same across all velocities
(not shown), of the same value at V = 0 under the label condition.