Dimo Ivanov1, Josef Pfeuffer2, Anna Gardumi1, Kâmil Uludağ3, and Benedikt A Poser1
1Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2Siemens Healthineers, Erlangen, Germany, 3Techna Institute & Koerner Scientist in MR Imaging, Joint Department of Medical Imaging and Krembil Brain Institute, Toronto, ON, Canada
1Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2Siemens Healthineers, Erlangen, Germany, 3Techna Institute & Koerner Scientist in MR Imaging, Joint Department of Medical Imaging and Krembil Brain Institute, Toronto, ON, Canada
Arterial spin labeling (ASL) fMRI is valuable, but suffers from low temporal signal-to-noise ratio (tSNR). We compared GRAPPA- and CAIPI-accelerated optimized short-TR single-shot 3D GRASE PASL and PCASL approaches at 3T to compare the effects of tSNR and number of samples on the fMRI results.
Figure 2: Single-subject perfusion tSNR maps and functional activation maps overlaid on the mean 3D GRASE images for PASL CAIPI (A,C) and PCASL CAIPI (B,D). Note the identical colorbar scaling for A and B and C and D, respectively.
Figure 3: Group mean and standard deviations of the grey matter control tSNR (A) and perfusion tSNR (B) efficiencies across labeling approaches and acceleration schemes.