Figure 1. a) An example of the shine-through effect in a healthy volunteer seen in the perfusion block of a fully acquired time-encoded pCASL (te-pCASL) dataset noticeable as negative signal in the large arteries and/or positive signal in higher slices. b) The temporal standard deviation (tStdv) of the same dataset shows that the effect (high tStdv in vessels) is present in all post-label-delays (PLDs) and that tStdv is an insightful measure of the effect.

Figure 4. ASL (subtracted) signal is shown for a single slice low in the brain, for the seven individual experiments in which RF (labeling) was enabled for single blocks only (columns). The separation of the individual blocks in each experiment can be seen in the black squares which have positive ASL signal. We observed that the shine-through artefact (red arrows) was visible in the disabled blocks, (negative or positive signal), and surprisingly, also in the experiment without any labeling at all (last column, experiment #8). See Figure 1 for explanation of the experiment numbers.