Joseph G. Woods1, Eric C. Wong1, David D. Shin2, and Divya Bolar1
1Department of Radiology, University of California San Diego, San Diego, CA, United States, 2GE Healthcare, Menlo Park, CA, United States
1Department of Radiology, University of California San Diego, San Diego, CA, United States, 2GE Healthcare, Menlo Park, CA, United States
A novel framework that minimizes eddy current artifacts in velocity-selective (VS) arterial spin labeling is introduced. The framework is applicable to any VS module design with no time penalty. Simulation and empirical data are presented with artifact reduction in phantom and human data.
Phantom error maps (% error) reflecting residual eddy current effects before and after VS gradient optimization, for DHRS and BIR8 VS labeling schemes. The bar graph reflects the mean absolute error across the phantom volume. Significant improvements are seen for the x, y, and z gradient axes for DHRS. The BIR-8 errors are small for each gradient axis, and little or no improvement was seen.
Human perfusion-weighted images acquired before and after VS gradient optimization for both DHRS and BIR-8 VS modules in x and y gradient directions. z direction was not acquired due to subject intolerance. Marked EC effects are seen for the standard DHRS approach, which are qualitatively improved after optimization. BIR-8 errors are small for each gradient axis, and little or no improvement was seen.
