Moss Y Zhao1, Audrey P Fan2, David Chen3,4, Jia Guo5, Yosuke Ishii6, David Shin7, Mohammad Mehdi Khalighi1, Dawn Holley1, Kim Halbert1, Andrea Otte1, Brittney Williams1, Jun-Hyung Park1, Bin Shen1, Gary Steinberg8, and Greg Zaharchuk1
1Radiology, Stanford University, Stanford, CA, United States, 2Biomedical Engineering and Neurology, University of California Davis, Davis, CA, United States, 3Medical Imaging, Taipei Medical University – Shuan-Ho Hospital, New Taipei City, Taiwan, 4Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 5Bioengineering, University of California Riverside, Riverside, CA, United States, 6Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan, 7GE Healthcare, Melo Park, CA, United States, 8Neurosurgery, Stanford University, Stanford, CA, United States
1Radiology, Stanford University, Stanford, CA, United States, 2Biomedical Engineering and Neurology, University of California Davis, Davis, CA, United States, 3Medical Imaging, Taipei Medical University – Shuan-Ho Hospital, New Taipei City, Taiwan, 4Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 5Bioengineering, University of California Riverside, Riverside, CA, United States, 6Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan, 7GE Healthcare, Melo Park, CA, United States, 8Neurosurgery, Stanford University, Stanford, CA, United States
ASL is effective in measuring CVR and can become a diagnostic tool to predict the risk of stroke for vasculopathy patients.
Figure 2: Structural and flow maps of an example patient. Occlusion are seen in right MCA and PCA territories in MRA of CoW and hyperintense focal spots in T2 FLAIR (marked by yellow arrows). In all PET and ASL modalities, CBF and CVR in the right MCA and PCA territories were lower than the right side.
Figure 1: Structural and flow maps of an example patient. Severe stenosis and occlusion are seen in left ACA and MCA territories in MRA of CoW and hyperintense focal spots in T2 FLAIR (indicated by yellow arrows). In all PET and ASL modalities, CBF and CVR in the left ACA and MCA territories were lower than the right side.