Prostate Perfusion Mapping using Fourier-Transform based Velocity-Selective Pulse Trains: Choice of Cutoff Velocity and Comparison with Brain
Dapeng Liu1,2, Dan Zhu3, Wenbo Li1,2, and Qin Qin1,2
1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 3Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States
Prostate blood flow and blood volume mapping
using VSASL prepared by Fourier-transform
based velocity-selective pulse trains were compared among different cutoff
velocities (Vc). The results suggest that lower Vc of VSASL is demanded for
prostate than for brain.
Figure 2: Brain (a) and prostate (b) PWS and corresponding
tSNR maps from one representative subject with four out of all ten slices. Both
blood flow (CBF for brain and PBF for prostate) and blood volume (CBV for brain
and PBV for prostate) maps were shown. M0
and DIR images were also shown above. Note that in the CBV PWS and tSNR images,
the CSF in leteral ventricles display dark as it has negative signal due to a
combination of long T2 values of CSF and the higher B1+ scale at the center of
the brain.
Figure 4: Averaged
blood flow PWS (a) and its tSNR (b), blood volume PWS (c) and its tSNR (d), in
ROIs of GM, WM and prostate from four subjects.