2807
MR Inversion Recovery Simulation and Scanning of Subjects with Focus on White Matter Lesion Contrast Optimization
Øystein Bech Gadmar1, Anne-Hilde Farstad2, Berit Elstad2, Piotr Sowa2, and Wibeke Nordhøy1
1Diagnostic Physics, Oslo University Hospital, Oslo, Norway, 2Radiology, Oslo University Hospital, Oslo, Norway
By modelling T2 prepared double inversion MR, a "True-T2" DIR sequence was found and tested that removes the undesired T1 contrast in fluid attenuated imaging therefore improving the desired T2 contrast between lesions both in WM and GM. Comparison with traditional FLAIR imaging was favorable.
Fluid attenuated IR images of a MS patient. Left/right: Sagittally acquired vs coronally reformatted images. Top panels: FLAIR. Bottom panels: True-T2 DIR of similar image planes. Multiple focal lesions are seen in the images, situated in deep WM as well as GM-associated.
Simulated True-T2 DIR sequence with a T2 preparation phase. Figure elements as in fig. 1; in addition an information box showing the simulator settings is included in the left panel. In the right panel is shown an information box showing signal and contrast strength and efficiency, that is, relative SNR/CNR per unit of acquisition time. The percentages shown refer to the corresponding ones in fig. 1.