Maria Gusseva1,2, Daniel Alexander Castellanos3, Mohamed Abdelghafar Hussein4,5, Joshua Greer 4, Gerald Greil4, Surendranath Veeram Reddy4, Dominique Chapelle1,2, Tarique Hussain4, and Radomir Chabiniok1,2,4,6
1Inria, Palaiseau, France, 2LMS, Ecole Polytechnique, Palaiseau, France, 3Department of Cardiology, Boston Children’s Hospital, Boston, MA, United States, 4Division of Pediatric Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, United States, 5Pediatric department, Kafrelsheikh University, Kafr Elsheikh, Egypt, 6Department of Mathematics, Czech Technical University in Prague, Faculty of Nuclear Sciences and Physical Engineering, Prague, Czech Republic
1Inria, Palaiseau, France, 2LMS, Ecole Polytechnique, Palaiseau, France, 3Department of Cardiology, Boston Children’s Hospital, Boston, MA, United States, 4Division of Pediatric Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, United States, 5Pediatric department, Kafrelsheikh University, Kafr Elsheikh, Egypt, 6Department of Mathematics, Czech Technical University in Prague, Faculty of Nuclear Sciences and Physical Engineering, Prague, Czech Republic
Patient-specific biophysical heart modeling was employed to resynchronize the intraventricular pressure and volume data acquired during combined cardiovascular MRI and catheterization procedure. Such model-filtered P-V loops allowed better clinical interpretation of iCMR exam.
Figure 1: Left: Single-heart cavity model coupled with the circulation system via system of diodes and a two-stage Windkessel. Right: Example of acquired and processed CMR and pressure data of LV rTOF patient #1.
