Altered cortico-cerebellar functional connectivity of language processing in congenital blind children
A Ankeeta1, S Senthil Kumaran1, and Rohit Saxena2
1Department of NMR & MRI Facility, All India Institute of Medical Sciences, Delhi, India, 2Dr RP Centre of Ophthalmology, All India Institute of Medical Sciences, Delhi, India
Congenitally blind subjects conscript visual cortex and cerebellum on functional
response to haptic language processing. Improved grey matter volume and duration of Braille
reading influences the functional connectivity of language network with cerebellum.
Figure 1. Illustration of
(A) independent component analysis for calculation of cortico-cerebellum during
semantic word recognition task in congenital blind relative to sighted control.
(B) Difference in cerebellar areas effect size and (C) estimation of gray
matter volume.
Table 2. Significant functional
connectivity of cerebellum and language integration estimated by using
independent component analysis for congenital blind children group as compared to
sighted control group.