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Investigating the relationship between temporal SNR and resting-state networks to evaluate the feasibility of fMRI at a low field MR scanner
Arjama Halder1,2, Demetrius Riberio de Paula3, William B Handler1, Andrea Soddu1, and Blaine A Chronik1,2
1xMR Labs, Physics and Astronomy, Western University, London, ON, Canada, 2Medical Biophysics, Western University, London, ON, Canada, 3Donders Institute, Radbound University, Nijmegen, Netherlands
Correlation coefficients for different resting-state networks and tSNR were found to linearly relate within a 95% confidence interval. The lower limit on tSNR will be calculated and used in future experiments with the 0.5T scanner.
Fig 4. Shows the Visual Occipital regions’ normalized Z values for a specific subject for (a) mean tSNR = 74.2 and (b) mean tSNR = 17.8 which causes the similarity index calculated between the normative database and volunteer’s data to drop from 73% in (a) to 62% in (b) within a 95% confidence interval.
Fig 3. Shows the correlation coefficient as a function of tSNR for an (a) Auditory region and (b) DMN region for each subject. The p-value for the linear regression is less than 0.05 indicating the fit statistically significant.