Ran Pang1,2, Xi Wu3, Yuchen Chi4, Rommy Elyan5, Xianke Luo6, Zhigang Chen6, Qingxian Yang2, Karunanayaka Prasanna7, and Kuncheng Li8
1Department of Radiology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 2Department of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, United States, 3Department of Acupuncture, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 4Department of Otolaryngology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 5Department of Radiology, Pennsylvania State University College of Medicine, PA, USA, Hershey, PA, United States, 6Department of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 7Department of Radiology, Pennsylvania State University College of Medicine, Hershey, PA, United States, 8Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China
1Department of Radiology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 2Department of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, United States, 3Department of Acupuncture, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 4Department of Otolaryngology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 5Department of Radiology, Pennsylvania State University College of Medicine, PA, USA, Hershey, PA, United States, 6Department of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, 7Department of Radiology, Pennsylvania State University College of Medicine, Hershey, PA, United States, 8Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China
Using verum and
sham acupunture treatments, and resting state fMRI, we've identified a unique
role and architecture for the cerebellum. It acts as a flexible, global hub
with a brain-wide influence that supports and maintains circadian rhythms
and sleep homeostasis.
Figure 2. (A)
Cerebellum mask (B &C) DC changes in cerebellum (8,9) is
correlated with sleep improvement (D) Insignificant DC changes between verum and
sham groups in cerebellum (8,9)
Figure 3. (A)
Functional connectivity (FC) between the cerebellum (8,9) seed and the thalamus
(B
& C) FC
changes in thalamus are correlated with sleep improvement in both groups (D) Significant
FC
changes between the verum and
sham groups in the thalamus (**p < 0.01).