Wenwen Gao1, Lei Du1, Bing Liu1, Yue Chen1, Yige Wang1, Xiuxiu Liu1, Lizhi Xie 2, and Guolin Ma1
1China-Japan Friendship Hospital, Beijing, China, 2GE healthcare, China, Beijing, China
1China-Japan Friendship Hospital, Beijing, China, 2GE healthcare, China, Beijing, China
Hemifacial spasm (HFS) is a motor disorder. The
purpose of this study was to investigate the functional alterations of the cortical-striatal
network in HFS using resting-state fMRI. To sum up, these data suggest that HFS may lead to an alteration of
neural activity of the cortical-striatal
loop.
Fig. 1: Differences of the cortical-striatal FC in patients with HFS compared to healthy controls. The FC between striatal subregions and both motor and emotion-related cortex was statistically different between the two groups (GRF correction, voxel P < 0.005, cluster P < 0.05). The yellow dots in the brain represent the seeds of striatal subregions. The red regions represent the increased FC between seeds and cortexes, while the blue areas represent a decreased FC. The color bar represents the t value.