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Alterations in regional and network-level neural function in patients with HCV infection and its association with cognitive dysfunction
Jia Yan Shi1, Zhong Shuai Zhang2, and Hua Jun Chen1
1Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China, 2SIEMENS Healthcare, Shanghai, China
This preliminary study presents additional evidence that HCV infection affects brain function, including local intrinsic neural activity and global functional integration.
Figure 1. Within-group ALFF maps in the healthy control (HC) group as well as the patients infected with hepatitis C virus (HCV). The letters “L” and “R” represent the left and right sides, respectively.
Figure 3. The functional connectivity pattern of seed region (i.e. left medial frontal gyrus and bilateral anterior cingulate gyrus) in the healthy control (HC group) and the patients with Hepatitis C Virus infection (HCV group). Compared with HC group, HCV group shows decreased functional connectivity between seed region and right middle frontal gyrus. The letters “L” and “R” represent the left and right sides, respectively.