3159
Brain structural and functional reorganization in tinnitus patients without hearing loss after sound therapy: a preliminary longitudinal study
Qian Chen1, Han Lv1, Zhaodi Wang2, and Zhenchang Wang1
1Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China, 2Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China
Idiopathic tinnitus patients experienced significant differences in auditory-related and nonauditory-related brain reorganization before and after sound therapy (narrow band noise), that is, sound therapy may have a significant effect on brain reorganization in patients with idiopathic tinnitus.

Figure4 Intergroup differences in internetwork FC between the tinnitus patients and HCs and between the patients before and after sound therapy.

(A) Compared with the HCs, the tinnitus patients exhibited a decreased (i.e., positive) (mVN and lVN) or an increased (i.e., less negative) (mVN and SMN; mVN and AN) internetwork FC at baseline.

Figure4 (B) Compared with HCs, tinnitus patients showed a decreased (i.e., positive) (AN and pDMN; DAN and LFPN) internetwork FC after sound therapy.