Jiawei Han1, Hui Zhang2, Junqi Xu2, Fanwen Wang2, Jian Gao3,4, Weibo Chen5, Hongmei Yan6, and He Wang1,2
1Human Phenome Institute, Fudan University, Shanghai, China, 2Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 3Department of Nutrition, Zhongshan Hospital, Fudan University, Shanghai, China, 4Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai, China, 5Philips Healthcare, Shanghai, China, 6Department of Endocrinology, Zhongshan Hospital, Fudan University, Shanghai, China
1Human Phenome Institute, Fudan University, Shanghai, China, 2Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 3Department of Nutrition, Zhongshan Hospital, Fudan University, Shanghai, China, 4Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai, China, 5Philips Healthcare, Shanghai, China, 6Department of Endocrinology, Zhongshan Hospital, Fudan University, Shanghai, China
Compared with diet control, acupuncture increase grey matter volume in physiological and psychological brain regions, where the impact on functional connectivity is even lighter after therapy. Acupuncture is likely to improve endocrine while reducing the pressure of weight loss.
Figure 1. (i) Regions wherein GMV are significantly
increased after acupuncture. The centers of 3 ROIs are MNI space coordinates of these clusters’ peak voxel
(ROI 1: (-38, -72, -35); ROI 2: (-5, -54, 8); ROI 3: (39, -41, 66)). (ii) Regions
wherein GMV are significantly increased after diet control therapy. The centers
of 2 ROIs are the MNI space coordinates of these clusters’ peak voxel (ROI 4:
(18, -9, -38); ROI 5: (-30, 47, 27)). P: Posterior; A: Anterior. Results (scan
2 – scan 1) are reported with a threshold of p < 0.001 (uncorrected) on the
voxel level and a cluster extent > 30 voxels.
Figure 2. The results of FC with 5 ROIs after acupuncture. A: Row 1 is the region wherein FC with ROI 2 are significantly increased and row 2 is the region wherein FC are decreased. B: The region wherein FC with ROI 3 are significantly decreased. C: The region wherein FC with ROI 4 are significantly increased. D: The region wherein FC with ROI 5 are significantly increased. L: Left; R: Right. Results (scan 2 – scan 1) are reported with a threshold of p < 0.001 (uncorrected) on the voxel level and a cluster extent ≥ 5 voxels.