Rajakumar Nagarajan1 and Gwenael Layec2
1Human Magnetic Resonance Center, Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, United States, 2Kinesiology, University of Massachusetts Amherst, Amherst, MA, United States
1Human Magnetic Resonance Center, Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, United States, 2Kinesiology, University of Massachusetts Amherst, Amherst, MA, United States
This
study provides the proof of concept for a non-invasive and localized method to
determine the alkaline Pi, a potential index of mitochondrial density at rest.
Figure
2. A 36 years old healthy volunteer 2D
CSI voxel location and selected single voxel spectrum and zoomed Pi region from
the tibialis anterior (red), soleus (yellow) and gastrocnemius (blue) muscles
Figure
1. A 36 years old healthy volunteer 2D
CSI voxel location and multivoxel spectra on top of T1W MRI