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Analysis of the diagnostic value of multimodal magnetic resonance imaging for non-small cell lung cancer
Ting Fang1, Nan Meng1, Meiyun Wang1,2, Zhun Huang2, Pengyang Feng2, Fangfang Fu3, Wei Wei3, Yaping Wu3, Yan Bai3, Jianmin Yuan4, Yang Yang5, and Hui Liu 6
1Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, 2Department of Radiology, Henan University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, 3Henan Provincial People’s Hospital, Zhengzhou, China, 4Central Research Institute, UIH Group, Shanghai, China, 5Central Research Institute, UIH Group, Beijing, China, 6UIH America, Inc. 9230 Kirby Dr. STE600, Houston, TX, United States
CEST can selectively label the exchangeable hydrogen protons in free macromolecules.IVIM can evaluate true water molecule diffusion and microcirculation perfusion . Our research shows that CEST and IVIM have similar diagnostic performance in the differential diagnosis of NSCLC.
Figure.1 :A 62-year-old man with left Lung adenocarcinoma. A is T2w map,B is D pseudo colored map,C is f pseudo colored map, D is D* pseudo colored maps,E is Calculated B0 map,F is MTRasym(3.5ppm) pseudo colored maps.
Figure.2: The MTRasym (3.5ppm), D, D*, and f values of adenocarcinoma and squamous cell carcinoma groups. (A) MTRasym (3.5ppm) = (22.04±12.87)%, (8.25±6.77)% ; (B) D = (1.33±0.44) ×10−3 mm2/s , (0.89± 0.16)×10−3 mm2/s ; (C) D* = (67.34±68.22)×10−3 mm2/s , (25.66±24.43)×10−3 mm2/s; (D) f = (0.34±0.18), (0.26±0.09) .