Lung Imaging with Tiny Golden Angle UTE in Mice
Anke Balasch1, Hao Li2, Patrick Metze1, Alireza Abaei2, and Volker Rasche1
1Department of Internal Medicine II, Ulm University Medical Center, Ulm, Germany, Ulm, Germany, 2Core Facility Small Animal Imaging (CF-SANI), Ulm University, Ulm, Germany, Ulm, Germany
Lung imaging in small animals is particular difficult
due to small anatomy dimensions, high respiratory and heart rate and the very
short T2* value in high magnetic fields. With 2D tyGA UTE it is feasible to generate lung
images in small rodents with sufficient quality to quantify PF and FV at 11.7T.
Figure 2: Proton fraction maps for EX and IN in coronal
and axial slice orientation. The grey lines indicate the position of the slice
in the respective other orientation.
Table 1: Proton fraction (PF) and SNR values (mean ± std) for the
coronal (a) and axial (b) slice orientation.