Prognostic value of MR imaging features derived from automatic segmentation in glioblastoma
Quan Dou1, Xue Feng1, Sohil Patel2, and Craig H. Meyer1
1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Radiology & Medical Imaging, University of Virginia, Charlottesville, VA, United States
In this study, we analyzed the relationships between glioblastoma patients overall survival and several automatic segmentation-based MR imaging features. Results showed that combining imaging features with clinical factors improved the survival prediction.
Figure 1. Deep learning-based automatic
segmentation. A pre-trained DCNN5 takes in pre- and post-contrast
T1-weighted, T2-weighted and T2-FLAIR images, and generates segmentation
results including three subregions: peritumoral edema, enhancing tumor, and
necrotic & non-enhancing tumor core.
Figure 3. Receiver operating characteristic
curve analyses for OS classification models.