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Exploring Brain Regions Involved in Working Memory using Interpretable Deep Learning
Mario Serrano-Sosa1, Jared Van Snellenberg2, and Chuan Huang2,3
1Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States, 2Psychiatry, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States, 3Radiology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, United States
We have developed an interpretable deep learning algorithm to predict working memory scores from 2-back fMRI data that was able to create averaged saliency maps highlighting regions most predictive of working memory scores.
Figure 3: Averaged saliency maps obtained after training and optimizing the CNN to predict WM subconstruct scores.
Figure 2: Network outputs for both CNN and KRR vs ground truth WM score. Blue dots are CNN outputs and black triangles are KRR outputs.