Sirisha Tadimalla1,2, Daniel J Wilson3, Margaret A Saysell4, Martin John Graves5, Iosif A Mendichovszky6,7, Geoffrey JM Parker8, and Steven Sourbron2,9
1Institute of Medical Physics, The University of Sydney, Sydney, Australia, 2Department of Biomedical Imaging Sciences, The University of Leeds, Leeds, United Kingdom, 3Department of Medical Physics and Engineering, Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom, 4Cardiac MRI, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5MR Physics and Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 6Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 7Department of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 8Bioxydyn, Manchester, United Kingdom, 9Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom
1Institute of Medical Physics, The University of Sydney, Sydney, Australia, 2Department of Biomedical Imaging Sciences, The University of Leeds, Leeds, United Kingdom, 3Department of Medical Physics and Engineering, Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom, 4Cardiac MRI, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5MR Physics and Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 6Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 7Department of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom, 8Bioxydyn, Manchester, United Kingdom, 9Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom
Bias, repeatability, and reproducibility of VFA T1 mapping in the liver in a multi-vendor setting were measured with a high degree of accuracy. The measurements are comparable to literature values in other organs and can serve as benchmark to qualify future methodological improvements.
Table 3. Repeatability and reproducibility of VFA T1 values in the liver, compared to literature values in phantoms and other organs.
Figure 1. Box plots showing median and inter-quartile ranges of (a) bias, (b) repeatability of VFA T1 values in all volunteers, averaged over both field strengths for each vendor, and (c) reproducibility calculated across all vendors as well as vendor pairs.* indicates significant difference p < 0.05